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Life Sciences Transformational R&D Investment Fund (TRIF) Pilot

The Life Sciences Transformational R&D Investment Fund (TRIF) Pilot is a grant of up to £25,000,000 for large private sector life sciences businesses in the UK that develop or manufacture medicines or medical devices. Open, no fixed deadline.

Run by Department for Science, Innovation and Technology

Checked against the official page (find-government-grants.service.gov.uk) on 5 Oct 2026.

The Life Sciences Transformational R&D Investment Fund Pilot offers capital grants to support large-scale R&D projects in the UK life sciences sector (eligible projects must exceed £100 million in total costs).

Apply or find out more Official page

These details are gathered from public web pages and are not financial advice. Check them with Department for Science, Innovation and Technology before you apply.

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Status and deadline

Status

Open

Confirmed on the official page

Deadline

Listed on Find a grant until 2028-03-31

Find a grant's listing date, not a confirmed deadline

How much

Up to £25,000,000

Whole fund: £50,000,000, shared between applicants

Confirmed on the official page

Who can apply

UK-registered wholly private sector businesses that operate as product developers, contract development and manufacturing organisations (CDMOs), or generics manufacturers, with two years of audited accounts and a track record of successfully developing or manufacturing medicines or medical devices. Projects must have a total cost of at least £100 million, be located in the UK, be primarily capital investment, be single company investments, and be dependent on the grant to proceed.

Confirmed on the official page

Business size

Large businesses

Not confirmed on the official page

Could your business apply?

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How to apply

Submit Expression of Interest (EOI) through online portal. Eligible projects invited to submit Application Form 1. Successful projects proceed to panel interview assessment of health resilience and innovation benefits, then Application Form 2 for financial and economic assessment.

Not confirmed on the official page

Where it is open: UK-wide

United Kingdom

Confirmed on the official page

HartlepoolMiddlesbroughRedcar and ClevelandStockton-on-TeesDarlingtonHaltonWarringtonBlackburn with DarwenBlackpoolKingston upon Hull, City ofEast Riding of YorkshireNorth East LincolnshireNorth LincolnshireYorkCounty DurhamCheshire EastCheshire West and ChesterNorthumberlandCumberlandWestmorland and FurnessNorth YorkshireBurnleyChorleyFyldeHyndburnLancasterPendlePrestonRibble ValleyRossendaleSouth RibbleWest LancashireWyreBoltonBuryManchesterOldhamRochdaleSalfordStockportTamesideTraffordWiganKnowsleyLiverpoolSt. HelensSeftonWirralDoncasterRotherhamNewcastle upon TyneNorth TynesideSouth TynesideSunderlandBradfordCalderdaleKirkleesLeedsWakefieldGatesheadBarnsleySheffield

Open across United Kingdom, so every council area in the North of England is shaded.

Drawn from the areas the funder names. If a scheme is only for part of a council area, check its own page. Boundaries from the Office for National Statistics.

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Source and last checked

Local Landscape gathers this information automatically from the pages below, then checks the key details against the official page. Checked against the official page (find-government-grants.service.gov.uk) on 5 Oct 2026. Its details last changed on 5 Oct 2026. No person has checked it, so confirm the details with Department for Science, Innovation and Technology before you apply.

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